XCell® ATF Device Size Selection Guide
Presented are hollow fiber filter areas, XCell® ATF Pump volumes, and typical bioreactor working volumes paired with each XCell ATF Device. Actual capacity and vessel size depend upon specific cell culture process conditions.
XCell ATF Single-use Tubing Sets
Filter Wetting Procedure
XCell ATF Single-use Devices are supplied dry. To ensure robust filter performance, it is important to wet the filter prior to use. The XCell ATF Tubing Set and the suggested wetting protocols are designed to:
- Ensure efficient and complete filter wetting by minimizing the formation of air pockets during the wetting process
- Enable pre-use filter integrity testing while maintaining sterility
- Provide a means for evaluating the sterility of the XCell ATF device prior to establishing the bioreactor connection
- Allow change-out of the XCell ATF device during a cell culture run without interrupting the bioreactor or XCell ATF operation
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| XCell® ATF 4 | XCell® ATF 6 | |
| Typical Bioreactor size (L) | 10 – 50 | 50 – 200 |
| Format | SS | SU, SS |
| Chemistry | PES, PS | PES, PS |
| Typical pore size SU | 0.2µ | 0.2µ |
| Typical pore size SS | 0.2µ, 0.5µ, 50KDa | 0.2µ, 0.5µ, 50KDa |
| Effective surface area (m2) | 0.77 | 2.5 |
| Filter height (cm) | 30 | 60 |
| Displacement volume (L) | 0.4 | 1.3 |
| ATF flow range (Lpm) | 3 – 8 | 10 – 20 |
| Typical scalable flow/fiber and filtrate rate | ||
| Controller | XCell Lab Scale Controller | XCell C410 Controller |
| XCell C410 Controller | XCell LS Controller | |
| XCell LS Controller | ||
